Adjustments related to prior year sales Gross To Net Adjustments Reserve Provision Related To Prior Period Sales Gross To Net Adjustments Reserve Provision Related To Prior Period Sales Rebates, Customer Fees/Credits, Co-Pay Assistance, and Other Rebates, Customer Fees, Credits, Co Pay Assistance, And Other [Member] Rebates, Customer Fees, Credits, Co Pay Assistance, And Other Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Range [Domain] Statistical Measurement [Domain] Unrealized losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Summary of Cash, Cash Equivalents and Investments Cash, Cash Equivalents and Investments [Table Text Block] Cover [Abstract] Cover [Abstract] Net increase in cash, cash equivalents, and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Trading Symbol Trading Symbol All Trading Arrangements All Trading Arrangements [Member] Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Number of core values supporting Segment Reporting, Number Of Core Values Supporting Operating Decisions Segment Reporting, Number Of Core Values Supporting Operating Decisions Non-NEOs Non-NEOs [Member] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Pay vs Performance Disclosure [Line Items] Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Customer B Customers B [Member] Customers B Trade receivables, net Increase (Decrease) in Accounts Receivable Variable Rate Component One Variable Rate Component One [Member] Variable Rate Component One Beneficial ownership threshold percentage Class Of Warrant Or Right, Beneficial Ownership, Exercise Threshold Class Of Warrant Or Right, Beneficial Ownership, Exercise Threshold Basic and Diluted Loss Per Common Share Earnings Per Share, Policy [Policy Text Block] Organization, Business and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Inventory Inventory, Policy [Policy Text Block] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Proceeds resulting from exercise of stock options Proceeds from Stock Options Exercised Line of credit facility, interest rate (as a percent) Line of Credit Facility, Interest Rate at Period End Award Timing Disclosures [Line Items] Other Performance Measure, Amount Other Performance Measure, Amount Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Shares available for future issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Lease liability Operating Lease, Liability, Noncurrent Stockholders' Equity (Deficit) Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Revenue from Contract with Customer [Abstract] Plan Name [Domain] Plan Name [Domain] Shares issued (in dollars per share) Sale of Stock, Price Per Share Proceeds from issuance or sale of equity Proceeds from Issuance or Sale of Equity Entity Tax Identification Number Entity Tax Identification Number Loan Facility, Tranche 4 Loan Facility, Tranche Four [Member] Loan Facility, Tranche Four Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Money Market Funds Money Market Funds [Member] Selling, general and administrative Selling, General and Administrative Expenses [Member] Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Cash received on stock transaction after deduction of issuance costs Sale of Stock, Consideration Received on Transaction Cash flows from operating activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Schedule of PSU Activity Share-Based Payment Arrangement, Performance Shares, Outstanding Activity [Table Text Block] Secured Debt Secured Debt [Member] Plan Name [Axis] Plan Name [Axis] Equity Components [Axis] Equity Components [Axis] Award Timing Method Award Timing Method [Text Block] Research and Development Costs Research and Development Expense, Policy [Policy Text Block] Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Fair value Debt Securities, Available-for-Sale Gross to net accrued liabilities Accrued Liabilities, Gross Accrued Liabilities, Gross Stock price discount per share (in dollars per share) Class Of Warrant Or Right, Stock Price Discount Per Common Share Class Of Warrant Or Right, Stock Price Discount Per Common Share Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Insider Trading Policies and Procedures [Line Items] Use of Estimates Use of Estimates, Policy [Policy Text Block] Amortization and interest accretion related to operating leases Operating Lease, Right-Of-Use Asset, Periodic Reduction (Increase) Operating Lease, Right-Of-Use Asset, Periodic Reduction (Increase) Adjustment to Compensation, Amount Adjustment to Compensation Amount Additional paid-in-capital Additional Paid in Capital, Common Stock Compensation Amount Outstanding Recovery Compensation Amount Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Entity Small Business Entity Small Business Eligible to Earn PSUs Eligible to Earn Performance Share [Member] Eligible to Earn Performance Share Accrued Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] Company Selected Measure Amount Company Selected Measure Amount Tabular List, Table Tabular List [Table Text Block] Unrecognized stock-based compensation expense Stock-based compensation expense Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Number of warrants issued for purchase of common shares (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Accrued liabilities Total accrued liabilities Accrued Liabilities, Current Antidilutive securities excluded from computation of earnings per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Credit Facility [Domain] Credit Facility [Domain] Corporate debt securities due within 1 to 2 years of date of purchase (Level 2) Corporate Debt Securities Due Within One To Two Years Of Date Of Purchase [Member] Corporate Debt Securities Due Within One To Two Years Of Date Of Purchase Cash, cash equivalents, and restricted cash at beginning of period Cash, cash equivalents, and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Unrecognized stock compensation expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Current assets: Assets, Current [Abstract] Fair Value of Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Authorized capital Share Repurchase Program, Authorized, Amount Inventory Inventory Disclosure [Text Block] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Product and Service [Domain] Product and Service [Domain] Common stock options Stock Options Stock options Share-Based Payment Arrangement, Option [Member] Vested (in dollars per share) PSUs attained (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Number of votes per share that common stockholders are entitled to receive Common Stock Voting Rights Number Represents the number of votes per share that common stockholders are entitled to receive. Warrants Warrant [Member] Security Exchange Name Security Exchange Name Basis spread on variable rate (as a percent) Debt Instrument, Basis Spread on Variable Rate Award Type [Axis] Award Type [Axis] Corporate Debt Securities Corporate Debt Securities [Member] Options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Revenue Benchmark Revenue from Contract with Customer, Product and Service Benchmark [Member] Research and development - external expense Research and Development External Expense Research and Development External Expense Work in process Inventory, Work in Process, Net of Reserves Property and equipment, net Property, Plant and Equipment, Net Total liabilities Liabilities Exercisable at the ending of the year (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Sale of stock received on transaction, gross Sale Of Stock, Consideration Received On Transaction, Gross Sale Of Stock, Consideration Received On Transaction, Gross Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Manufacturing and drug supply Accrued Manufacturing and Drug Supply Current Accrued manufacturing and drug supply Current. Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Expiration Date Trading Arrangement Expiration Date Cash flows from investing activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward] Lease liability Operating Lease, Liability, Current Total Shareholder Return Amount Total Shareholder Return Amount Common stock, shares issued (in shares) Balance (in shares) Balance (in shares) Common Stock, Shares, Issued Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Additional drawn Line of Credit Facility, Maximum Borrowing Capacity Concentration risk, percentage (as a percent) Concentration Risk, Percentage 2024 Public Stock Offering Public Offering, 2024 [Member] Public Offering, 2024 Cost Cash, Cash Equivalents, and Short-term Investments, At Cost This item represents the cost of debt and equity securities, which are categorized neither as held-to-maturity nor trading, net of adjustments including accretion, amortization, collection of cash, previous other-than-temporary impairments recognized in earnings, and cash and cash equivalents. Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Debt Instrument [Line Items] Commitments and Contingencies Debt Instrument [Line Items] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Research and development Research and Development Expense [Member] Weighted average exercise price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Loan Facility, Tranches 2 and 3 Loan Facility, Tranches Two and Three [Member] Loan Facility, Tranches Two and Three Cash Cash [Member] Unrealized loss on available-for-sale securities Unrealized loss on marketable securities OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax Diluted weighted average number of common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Paul Friedman [Member] Paul Friedman Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Line of credit facility, increase In maximum borrowing capacity Line Of Credit Facility, Increase In Maximum Borrowing Capacity Line Of Credit Facility, Increase In Maximum Borrowing Capacity MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Minimum liquidity covenant Debt Instrument, Covenant, Liquidity, Minimum Debt Instrument, Covenant, Liquidity, Minimum Debt instrument, covenant, market capitalization minimum Debt Instrument, Covenant, Market Capitalization Minimum Debt Instrument, Covenant, Market Capitalization Minimum Long-Term Debt, Type [Axis] Long-Term Debt, Type [Axis] Total stockholders’ equity Balance Balance Equity, Attributable to Parent Liquidity and Uncertainties Liquidity and Uncertainties Liquidity And Uncertainties Disclosure Abstract Proceeds from issuance of debt Proceeds from Issuance of Debt Related Party Related Party [Member] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Selling, general and administrative Selling, general and administrative Selling, General and Administrative Expense Unrealized loss on marketable securities and foreign currency Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Trade receivables, net Accounts Receivable, after Allowance for Credit Loss, Current Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Accrued interest payments, term (in months) Debt Instrument, Accrued Interest Payments, Term Debt Instrument, Accrued Interest Payments, Term Sale of Stock [Domain] Sale of Stock [Domain] Anti-dilutive securities Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Loans payable, net of discount Long-Term Debt Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Document Fiscal Period Focus Document Fiscal Period Focus All Executive Categories All Executive Categories [Member] Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Assets Assets [Abstract] Restricted cash Restricted Cash, Current Document Type Document Type Term charges on aggregate principal amount, (as a percent) Line of Credit Facility, Commitment Fee Percentage Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Schedule of Segment Information Schedule of Segment Reporting Information, by Segment [Table Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Less amount representing interest Interest Expense, Debt, Excluding Amortization Nonrelated Party Nonrelated Party [Member] 2015 Stock Plan And Inducement Plan Two Thousand And Fifteen Stock And Inducement Plan [Member] Two thousand and fifteen stock and inducement plan. Vested (in shares) PSUs attained (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Cost Debt Securities, Available-for-Sale, Amortized Cost Hoffmann-La Roche ("Roche") Hoffman La Roche [Member] Represents information pertaining to Hoffman-La Roche. Maximum Maximum [Member] Marketable securities: Debt Securities, Available-for-Sale [Abstract] Long term debt floor interest rate (as a percent) Long Term Debt Floor Interest Rate Percentage Long term debt floor interest rate percentage. Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Intangible assets, net Finite-Lived Intangible Assets, Net Antidilutive Securities [Axis] Antidilutive Securities [Axis] Accounts payable Accounts Payable, Current Loan Facility, Tranche 3 Loan Facility, Tranche Three [Member] Loan Facility, Tranche Three Accounting Policies [Abstract] Accounting Policies [Abstract] Revenues: Revenues [Abstract] Less unamortized discount Debt Instrument, Unamortized Discount Current Fiscal Year End Date Current Fiscal Year End Date Statistical Measurement [Axis] Statistical Measurement [Axis] PEO Name PEO Name Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Equity Award [Domain] Award Type [Domain] Name Outstanding Recovery, Individual Name Provision related to sales in the current year Gross To Net Adjustments Reserve Provision Related To Current Period Sales Gross To Net Adjustments Reserve Provision Related To Current Period Sales Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Non-PEO NEO Non-PEO NEO [Member] Additional paid-in Capital Additional Paid-in Capital [Member] Award Timing Predetermined Award Timing Predetermined [Flag] Unrealized foreign currency gain Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Gain (Loss), before Reclassification and Tax Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Class of Stock [Axis] Class of Stock [Axis] Diluted net loss per common share (in dollars per share) Earnings Per Share, Diluted Counterparty Name [Domain] Counterparty Name [Domain] Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Name Measure Name Entity Interactive Data Current Entity Interactive Data Current Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Fair value Cash, Cash Equivalents, and Short-Term Investments Intangible Assets Intangible Assets, Finite-Lived, Policy [Policy Text Block] Research and development - personnel and internal expense Research ​And ​Development​ Expense, Personnel And Internal Research ​And ​Development​ Expense, Personnel And Internal Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Customer [Axis] Customer [Axis] Valuation allowance on deferred tax assets (as a percent) Deferred Tax Assets, Percentage Of Valuation Allowance The percentage of valuation allowance on the deferred tax assets. Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Convertible Series A and B Preferred Stock Convertible Series A and B Preferred Stock [Member] Convertible Series A and B Preferred Stock [Member] Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Research, Development and Commercialization Agreement Research Development And Commercialization Agreement [Member] Represents information pertaining to Research, Development and Commercialization Agreement with Hoffmann-La Roche ("Roche") which grants a sole and exclusive license to develop, use, sell, offer for sale and import any Licensed Product as defined by the agreement. Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Marketable securities Debt Securities, Available-for-Sale, Current Schedule of Investments [Line Items] Schedule of Investments [Line Items] Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Weighted average remaining period (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Product revenue, net Revenue from Contract with Customer, Excluding Assessed Tax Acquisition of intangible asset Payments to Acquire Intangible Assets Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Milestone payment due Collaborative Arrangement, Contingent Consideration, Liability, Milestone Payment Collaborative Arrangement, Contingent Consideration, Liability, Milestone Payment Net cash provided by investing activities Net Cash Provided by (Used in) Investing Activities Loss from operations Operating Income (Loss) Interest expense Interest Expense, Operating and Nonoperating Research and development Research and Development Expense (Excluding Acquired in Process Cost) Number of reportable segments Number of Reportable Segments Total liabilities and stockholders’ equity Liabilities and Equity Rebecca Taub [Member] Rebecca Taub Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] All Adjustments to Compensation All Adjustments to Compensation [Member] Compensation and benefits Employee-related Liabilities, Current Marketable Securities Marketable Securities, Policy [Policy Text Block] Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Other segment income (expense) Interest Income (Expense), Nonoperating Interest income Investment Income, Interest Schedule of RSU Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Schedule of Maturities of Long-Term Debt Schedule of Maturities of Long-Term Debt [Table Text Block] Summary of Significant Accounting Policies Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Obtaining a right-of-use asset in exchange for a lease liability Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Underlying Security Market Price Change Underlying Security Market Price Change, Percent Individual: Individual [Axis] Accumulated other comprehensive income (loss) AOCI Attributable to Parent [Member] Options cancelled (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Customer A Customer A [Member] Customer A Restricted cash Restricted Cash Inventory Total Inventory, Net Long-Term Debt, Type [Domain] Long-Term Debt, Type [Domain] Product and Service [Axis] Product and Service [Axis] Entity Address, State or Province Entity Address, State or Province Statement Statement [Line Items] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Line of credit facility, number of withdrawals upon milestone achievements Line of Credit Facility, Number Of Withdrawals Upon Milestone Achievements Line of Credit Facility, Number Of Withdrawals Upon Milestone Achievements Chargebacks, Discounts for Prompt Pay and Other Allowances Chargebacks, Discounts for Prompt Pay and Other Allowances [Member] Chargebacks, Discounts for Prompt Pay and Other Allowances Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Major Types of Debt and Equity Securities [Domain] Financial Instruments [Domain] Weighted average grant date fair value (in dollars per share) Unvested, beginning balance (in dollars per share) Unvested, ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Liabilities and Stockholders’ Equity Liabilities and Equity [Abstract] Beneficial ownership notice period (in days) Class Of Warrant Or Right, Beneficial Ownership, Exercise Percentage Notice Period Class Of Warrant Or Right, Beneficial Ownership, Exercise Percentage Notice Period Restatement Determination Date Restatement Determination Date Public Stock Offering Public Stock Offering [Member] Public Stock Offering 2021 Sales Agreement Two Thousand and Twenty One Sales Agreement [Member] Two thousand and twenty one sales agreement. Adoption Date Trading Arrangement Adoption Date Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Cowen & Co. LLC Cowen Co. Llc [Member] Represent of Cowen & Co. LLC Member. 2023 Inducement Plan Inducement Plan 2023 [Member] Two Thousand And Twenty Three Stock Inducement Plan [Member] Contract with Customer, Asset, Allowance for Credit Loss [Roll Forward] Contract with Customer, Asset, Allowance for Credit Loss [Roll Forward] Outstanding at the beginning of the year (in dollars per share) Outstanding at the ending of the year (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Concentration Risk [Table] Concentration Risk [Table] Right-of-use asset Operating Lease, Right-of-Use Asset Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Outstanding at the beginning of the year (in shares) Outstanding at the ending of the year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Purchasing period Sale Of Stock, Purchasing Period Sale Of Stock, Purchasing Period Long-term debt Long-Term Debt, Gross Exercise Price Award Exercise Price Variable Rate Component Two Variable Rate Component Two [Member] Variable Rate Component Two Arrangement Duration Trading Arrangement Duration Sale of warrants to related parties in equity offerings, exercise of common stock options, and restricted stock vesting, net of transaction costs Stock Issued During Period, Value, Stock Options Exercised Operating expenses: Costs and Expenses [Abstract] Stockholders’ equity: Equity, Attributable to Parent [Abstract] Granted (in dollars per share) PSUs granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Liquidity and Uncertainties Substantial Doubt about Going Concern [Text Block] Income Taxes Income Tax, Policy [Policy Text Block] Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Accounts payable Increase (Decrease) in Accounts Payable, Trade All Individuals All Individuals [Member] PEO PEO [Member] Income Taxes Income Tax Disclosure [Abstract] Name Trading Arrangement, Individual Name Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Number of office lease amendment Number Of Amendments Number Of Amendments 2015 Stock Plan Stock Plan 2015 [Member] Two thousand and fifteen stock plan Unrealized gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax 2025 Long-Term Debt, Maturity, Remainder of Fiscal Year Cost of sales Operating Costs and Expenses Schedule of Concentrations of Credit Risk and Significant Customers Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Common stock granted and issuable (in shares) Common Stock, Capital Shares Granted And Issuable Common Stock, Capital Shares Granted And Issuable Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Common stock, capital shares reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Related and Nonrelated Parties [Domain] Related and Nonrelated Parties [Domain] Total cash and cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Intangible assets in accounts payable at the end of the period Intangible Assets In Accounts Payable Intangible Assets In Accounts Payable Total long term liabilities Liabilities, Noncurrent Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Cash, Cash Equivalents, Restricted Cash, and Marketable Securities Cash, Cash Equivalents, and Marketable Securities [Text Block] Local Phone Number Local Phone Number Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Total operating expenses Operating Expenses Stock-based compensation expense related to equity-classified awards APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Long term liabilities: Liabilities, Noncurrent [Abstract] Line of credit facility, increase (decrease) Line of Credit Facility, Increase (Decrease), Net PEO Total Compensation Amount PEO Total Compensation Amount Preferred stock conversion ratio (in shares) Preferred Stock, Convertible, Conversion Ratio Schedule of Accrued Liabilities Schedule of Accrued Liabilities [Table Text Block] Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Axis] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Sales and maturities of marketable securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Debt Disclosure [Abstract] Debt Disclosure [Abstract] Common stock Common Stock [Member] Measure: Measure [Axis] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Patents Patents [Policy Text Block] Disclosure of accounting policy for patents. Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs (in shares) Stock Issued During Period, Shares, New Issues Line of Credit Line of Credit [Member] Entity Emerging Growth Company Entity Emerging Growth Company Segment Reporting [Abstract] Entity Central Index Key Entity Central Index Key Provision for excess inventory Provision For Excess Inventory Provision For Excess Inventory Schedule of Inventory Schedule of Inventory, Current [Table Text Block] Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Loan Facility, Tranche 1 Loan Facility, Tranche One [Member] Loan Facility, Tranche One Stockholders' Equity Equity [Text Block] Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Equity Component [Domain] Equity Component [Domain] Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Loan Facility Loan Facility [Member] Loan facility member. Financial Instrument [Axis] Financial Instrument [Axis] Segment Information Segment Reporting Disclosure [Text Block] Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Entity Shell Company Entity Shell Company Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Comprehensive Income (Loss) Comprehensive Income, Policy [Policy Text Block] Title Trading Arrangement, Individual Title Statement [Table] Statement [Table] Counterparty Name [Axis] Counterparty Name [Axis] Other clinical study related costs Accrued Other Clinical Study Related Costs Current Accrued other clinical study related costs current. City Area Code City Area Code Current liabilities: Liabilities, Current [Abstract] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Schedule Of Gross To Net Adjustments Reserve Schedule Of Gross To Net Adjustments Reserve [Table Text Block] Schedule Of Gross To Net Adjustments Reserve Total current assets Assets, Current U.S. government and government sponsored entities due within 1 year of date of purchase (Level 2) US Treasury And Government Due Within One Year [Member] US Treasury And Government Due Within One Year Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Preferred stock Preferred stock Preferred Stock [Member] Accrued liabilities Increase (Decrease) in Accrued Liabilities Exercisable at the ending of the year (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Payments and customer credits issued Gross To Net Adjustments Reserve Credits And Payments Made Gross To Net Adjustments Reserve Credits And Payments Made Hercules Warrants Hercules Warrants [Member] Hercules Warrants Schedule of Long-Term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Loan payable, net of discount Long-Term Debt, Excluding Current Maturities Weighted average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted-average grant date fair value of options (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Net loss per common share: Earnings Per Share [Abstract] Equity [Abstract] Raw materials Inventory, Raw Materials, Net of Reserves Accumulated deficit Retained Earnings (Accumulated Deficit) Class of Stock [Domain] Class of Stock [Domain] Inventory Increase (Decrease) in Inventories 2027 Long-Term Debt, Maturity, Year Two Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Equity Awards Adjustments Equity Awards Adjustments [Member] Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Underlying Securities Award Underlying Securities Amount Performance-based restricted stock units Performance-Based Restricted Stock Units (PSUs) Performance-based restricted stock units Performance Shares [Member] Credit Facility [Axis] Credit Facility [Axis] Amendment Flag Amendment Flag Entity Registrant Name Entity Registrant Name Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Depreciation and amortization expense Depreciation, Depletion and Amortization Fair Value as of Grant Date Award Grant Date Fair Value Customer Concentration Risk Customer Concentration Risk [Member] Selling, General and Administrative Expenses Selling, General and Administrative Expenses, Policy [Policy Text Block] Number of shares issued in transaction (in shares) Sale of Stock, Number of Shares Issued in Transaction Long Term Debt Debt Disclosure [Text Block] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Debt instrument, face amount Debt Instrument, Face Amount Issuance of common shares and sale of warrants in equity offerings, excluding to related parties, net of transaction costs Stock Issued During Period, Value, New Issues Entity Address, Postal Zip Code Entity Address, Postal Zip Code Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Variable Rate Component [Axis] Variable Rate Component [Axis] Variable Rate Component Principle of Consolidation Consolidation, Policy [Policy Text Block] Restatement Determination Date: Restatement Determination Date [Axis] Arrangements and Non-arrangement Transactions [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Title of 12(b) Security Title of 12(b) Security Concentration Risk Type [Axis] Concentration Risk Type [Axis] Common stock, par value $0.0001 per share authorized: 200,000,000 at March 31, 2025 and December 31, 2024; 22,187,716 and 22,004,679 shares issued and outstanding at March 31, 2025 and December 31, 2024, respectively Common Stock, Value, Issued Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Schedule of Investments [Table] Schedule of Investments [Table] Remainder of future milestone payments Remaining Milestone Payments The amount of future milestone payments remaining to be paid under the agreement. Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Accrued Liabilities, Current [Abstract] Accrued Liabilities, Current [Abstract] Forfeited (in dollars per share) PSUs forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Cash flows from financing activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Concentration Risk [Line Items] Concentration Risk [Line Items] Preferred stock, par value $0.0001 per share authorized: 5,000,000 shares at March 31, 2025 and December 31, 2024; 2,369,797 and 2,369,797 shares issued and outstanding at March 31, 2025 and December 31, 2024, respectively Preferred Stock, Value, Issued Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Loan Facility, Tranche 2 Loan Facility, Tranche Two [Member] Loan Facility, Tranche Two Basic net loss per common share (in dollars per share) Earnings Per Share, Basic Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Expiration period (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Beneficial ownership maximum percentage Class Of Warrant Or Right, Beneficial Ownership, Maximum Threshold Class Of Warrant Or Right, Beneficial Ownership, Maximum Threshold Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Total current liabilities Liabilities, Current Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Balance, beginning Balance, ending Gross To Net Adjustments Reserve Gross To Net Adjustments Reserve Total assets Assets Cost of sales Cost of Goods and Services Sold Granted (in shares) PSUs granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Over-Allotment Option Over-Allotment Option [Member] US government and government sponsored entities (Level 1) US Treasury and Government [Member] Cash and Cash Equivalents [Abstract] Cash and Cash Equivalents [Abstract] Purchases of property and equipment, net of disposals Payments to Acquire Property, Plant, and Equipment Thereafter Long-Term Debt, Maturity After Year Two Long-Term Debt, Maturity After Year Two US government and government sponsored entities due within 1 to 2 years of date of purchase (Level 2) US Treasury And Government Due Within One To Two Years [Member] US Treasury And Government Due Within One To Two Years Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Stock-Based Compensation Share-Based Payment Arrangement [Policy Text Block] Termination Date Trading Arrangement Termination Date Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Class of warrant or right, exercise price of warrants or rights (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Product revenue, net Revenues 2026 Long-Term Debt, Maturity, Year One Stock-based Compensation Share-Based Payment Arrangement [Text Block] Entity Address, City or Town Entity Address, City or Town Leases Lessee, Leases [Policy Text Block] Debt Instrument [Axis] Debt Instrument [Axis] Schedule of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Total intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Contract research organization costs Accrued Contract Research Costs Current Accrued Contract Research Costs, Current. Accrued interest, net of interest received on maturity of investments Increase (Decrease) In Accrued Interest, Net Of Interest Received The increase (decrease) during the reporting period in the aggregate amount of accrued interest expense incurred but not yet paid, net of interest received on maturity of investments. Stock-based compensation expense Share-Based Payment Arrangement, Expense Net loss Net Loss Net loss Net Income (Loss) Attributable to Parent Trading Arrangement: Trading Arrangement [Axis] Options granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Forfeited (in shares) PSUs forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Line of credit facility, current borrowing capacity Line of Credit Facility, Current Borrowing Capacity Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Maximum aggregate offering price Common Stock Aggregate Offering Price Represents the maximum aggregate offering price the entity may issue and sell shares of its common stock from time to time, at the entity's option, according to at-the-market issuance sales agreement with third party. Entity File Number Entity File Number Two Thousand and Twenty Two Registered Direct Offering Two Thousand and Twenty Two Registered Direct Offering [Member] Two Thousand and Twenty Two Registered Direct Offering [Member] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Product Revenue, Net Revenue from Contract with Customer [Text Block] Document Fiscal Year Focus Document Fiscal Year Focus Income Statement [Abstract] Income Statement [Abstract] Entity Address, Address Line One Entity Address, Address Line One Pre-funded warrants Pre Funded Warrants [Member] Pre FundedWarrants [Member] Entity Address, Address Line Two Entity Address, Address Line Two Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Other Other Accrued Liabilities, Current Name Forgone Recovery, Individual Name Line of credit facility, decrease In maximum borrowing capacity Line Of Credit Facility, Decrease In Maximum Borrowing Capacity Line Of Credit Facility, Decrease In Maximum Borrowing Capacity Document Period End Date Document Period End Date Sale of Stock [Axis] Sale of Stock [Axis] Finished goods Inventory, Finished Goods, Net of Reserves Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Equity award other than options, nonvested (in shares) Outstanding, beginning balance (in shares) Outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Insider Trading Arrangements [Line Items] Inventory Disclosure [Abstract] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Warrants and rights outstanding Warrants and Rights Outstanding Adjustment to Compensation: Adjustment to Compensation [Axis] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Customer C Customers C [Member] Customers C Document Transition Report Document Transition Report Document Quarterly Report Document Quarterly Report Purchase obligation Purchase Obligation Variable Rate Component [Domain] Variable Rate Component [Domain] Variable Rate Component [Domain] Customer [Domain] Customer [Domain] Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax Entity Current Reporting Status Entity Current Reporting Status Accumulated deficit Retained Earnings [Member] Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Related and Nonrelated Parties [Axis] Related and Nonrelated Parties [Axis] Basic weighted average number of common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Preferred shares number voting rights Preferred Stock, Number Of Voting Rights Number of voting rights of preferred stock. Includes eligibility to vote and votes per share owned. Include also, if any, unusual voting rights. Customer D Customers D [Member] Customers D 2024 Sales Agreement 2024 Sales Agreement [Member] 2024 Sales Agreement Restricted stock units Restricted Stock Units (RSUs) Restricted stock units Restricted Stock Units (RSUs) [Member] Realized gains or losses on marketable securities Debt Securities, Available-for-Sale, Realized Gain (Loss) Amortization of debt issuance costs and discount Amortization of Debt Issuance Costs and Discounts Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Professional fees Accrued Professional Fees, Current Executive Category: Executive Category [Axis] Name Awards Close in Time to MNPI Disclosures, Individual Name Options cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Entity Filer Category Entity Filer Category Statement of Income Location, Balance [Domain] Statement of Income Location, Balance [Domain] Purchases of marketable securities Payments to Acquire Debt Securities, Available-for-Sale Company Selected Measure Name Company Selected Measure Name