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Organization, Business, and Basis of Presentation </div></div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 6pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Organization and Business </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Madrigal Pharmaceuticals, Inc. (the “Company” or “Madrigal”) is a clinical-stage pharmaceutical company developing novel, high-quality, small-molecule drugs addressing major unmet needs in cardiovascular, metabolic, and liver diseases. The Company’s lead compound, <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">MGL-3196</div> (resmetirom), is being advanced for <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-alcoholic</div> steatohepatitis (“NASH”), a liver disease that commonly affects people with metabolic diseases such as obesity and diabetes, and <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-alcoholic</div> fatty liver disease (“NAFLD”). The Company initiated a Phase 2 study of resmetirom in NASH in October 2016. In February 2017, the Company initiated a Phase 2 study of resmetirom in patients with Heterozygous Familial Hypercholesterolemia (“HeFH”). Both Phase 2 studies were fully enrolled in 2017, the HeFH study was completed in February 2018, and the NASH study was completed in May 2018. The Company initiated a Phase 3 study of resmetirom in NASH in March 2019. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Madrigal was originally incorporated as a private company (“Private Madrigal”) on August 19, 2011 and operations commenced in September 2011. On July 22, 2016, Private Madrigal completed a reverse merger (the “Merger”) into Synta Pharmaceuticals Corp. (“Synta”). Upon the consummation of the Merger, the historical financial statements of Private Madrigal became the Company’s historical financial statements. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Basis of Presentation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States (“GAAP”) have been condensed or omitted. Accordingly, the unaudited condensed consolidated financial statements do not include all information and footnotes required by GAAP for complete annual financial statements. However, we believe that the disclosures included in these financial statements are adequate to make the information presented not misleading. The unaudited condensed financial statements, in the opinion of management, reflect all adjustments, which include normal recurring adjustments, necessary for a fair statement of such interim results. The interim results are not necessarily indicative of the results that we will have for the full year ending December 31, 2019 or any subsequent period. These unaudited condensed financial statements should be read in conjunction with the audited consolidated financial statements and the notes to those statements for the year ended December 31, 2018. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2. Summary of Significant Accounting Policies </div></div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 6pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Principle of Consolidation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The consolidated financial statements include the financial statements of the Company and its wholly owned subsidiaries. All significant intercompany balances have been eliminated in consolidation. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Use of Estimates </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect certain reported amounts of assets and liabilities, and the reported amounts of revenues and expenses during the reporting periods. The Company bases its estimates on historical experience and various other assumptions that management believes to be reasonable under the circumstances. Changes in estimates are recorded in the period in which they become known. Actual results could ​​​​​​​differ from those estimates. </div></div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and Cash Equivalents </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company considers all highly liquid investments with original maturities of three months or less at the date of purchase to be cash equivalents. The Company maintains its cash in bank accounts, the balance of which, at times, exceeds Federal Deposit Insurance Corporation insured limits. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The primary objective of the Company’s investment activities is to preserve its capital for the purpose of funding operations and the Company does not enter into investments for trading or speculative purposes. The Company’s cash is deposited in highly rated financial institutions in the United States. The Company invests in money market funds and high-grade, commercial paper and corporate bonds, which management believes are subject to minimal credit and market risk. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: 12pt;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable Securities </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Marketable securities consist of investments in high-grade corporate obligations and government and government agency obligations that are classified as <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale.</div> Since these securities are available to fund current operations, they are classified as current assets on the consolidated balance sheets.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;">The Company adjusts the cost of <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> debt securities for amortization of premiums and accretion of discounts to maturity. The Company includes such amortization and accretion as a component of interest income, net. Realized gains and losses and declines in value, if any, that the Company judges to be other-than-temporary on <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> securities are reported as a component of interest income, net. To determine whether an other-than-temporary impairment exists, the Company considers whether it intends to sell the debt security and, if the Company does not intend to sell the debt security, it considers available evidence to assess whether it is more likely than not that it will be required to sell the security before the recovery of its amortized cost basis. During the three and nine months ended September 30, 2019 and 2018, the Company determined it did not have any securities that were other-than-temporarily impaired.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities are stated at fair value, including accrued interest, with their unrealized gains and losses included as a component of accumulated other comprehensive income or loss, which is a separate component of stockholders’ equity. The fair value of these securities is based on quoted prices and observable inputs on a recurring basis. Realized gains and losses are determined on the specific identification method. During the three and nine months ended September 30, 2019 and 2018, the Company did not have any realized gains or losses on marketable securities. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair Value of Financial Instruments </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The carrying amounts of the Company’s financial instruments, which include cash equivalents, and marketable securities, approximate their fair values. The fair value of the Company’s financial instruments reflects the amounts that would be received upon sale of an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The fair value hierarchy has the following three levels: </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 1—quoted prices in active markets for identical assets and liabilities. </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 2—observable inputs other than Level 1 inputs. Examples of Level 2 inputs include quoted prices in active markets for similar assets or liabilities and quoted prices for identical assets or liabilities in markets that are not active. </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 3—unobservable inputs that reflect the Company’s own assumptions about the assumptions market participants would use in pricing the asset or liability. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Financial assets and liabilities are classified in their entirety within the fair value hierarchy based on the lowest level of input that is significant to the fair value measurement. The Company measures the fair value of its marketable securities by taking into consideration valuations obtained from third-party pricing sources. The pricing services utilize industry standard valuation models, including both income and market based approaches, for which all significant inputs are observable, either directly or indirectly, to estimate fair value. These inputs include reported trades of and broker-dealer quotes on the same or similar securities, issuer credit spreads, benchmark securities and other observable inputs. As of September 30, 2019, the Company’s financial assets valued based on Level 1 inputs consisted of cash and cash equivalents in a money market fund and its financial assets valued based on Level 2 inputs consisted of high-grade corporate bonds and commercial paper. During the three and nine months ended September 30, 2019 and 2018, the Company did not have any transfers of financial assets between Levels 1 and 2. As of September 30, 2019 and December 31, 2018, the Company did not have any financial liabilities that were recorded at fair value on a recurring basis on the balance sheet. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Research and Development Costs </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Research and development costs are expensed as incurred. Research and development costs are comprised of costs incurred in performing research and development activities, including internal costs (including stock-based compensation), costs for consultants, milestone payments under licensing agreements, and other costs associated with the Company’s preclinical and clinical programs. In particular, the Company has conducted safety studies in animals, optimized and implemented the manufacturing of our drug, and conducted Phase <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">1-3</div> clinical trials, all of which are considered research and development expenditures. Significant judgment and estimates are made in determining the amount of research and development costs recognized in each reporting period. The Company analyzes the progress of its clinical trials, completion of milestones under its license agreements, invoices received and contracted costs when estimating research and development costs. Actual results could differ from the Company’s estimates. The Company’s historical estimates for research and development costs have not been materially different from the actual costs.</div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Patents </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Costs to secure and defend patents are expensed as incurred and are classified as general and administrative expense in the Company’s consolidated statements of operations. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-Based Compensation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">The Company recognizes stock-based compensation expense based on the grant date fair value of stock options granted to employees, officers, and directors. The Company uses the Black-Scholes option pricing model to determine the grant date fair value as management believes it is the most appropriate valuation method for its option grants. The Black-Scholes model requires inputs for risk-free interest rate, dividend yield, volatility and expected lives of the options. The expected lives for options granted represent the period of time that options granted are expected to be outstanding. The Company uses the simplified method for determining the expected lives of options. Expected volatility is based upon an industry estimate or blended rate including the Company’s historical trading activity. The risk-free rate for periods within the expected life of the option is based on the U.S. Treasury yield curve in effect at the time of the grant. The Company estimates the forfeiture rate based on historical data. This analysis is <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">re-evaluated</div> at least annually and the forfeiture rate is adjusted as necessary.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Certain of the employee stock options granted by the Company are structured to qualify as incentive stock options (“ISOs”). Under current tax regulations, the Company does not receive a tax deduction for the issuance, exercise or disposition of ISOs if the employee meets certain holding requirements. If the employee does not meet the holding requirements, a disqualifying disposition occurs, at which time the Company may receive a tax deduction. The Company does not record tax benefits related to ISOs unless and until a disqualifying disposition is reported. In the event of a disqualifying disposition, the entire tax benefit is recorded as a reduction of income tax expense. The Company has not recognized any income tax benefit for its share-based compensation arrangements due to the fact that the Company does not believe it is more likely than not it will realize the related deferred tax assets. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Income Taxes </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company uses the asset and liability method to account for income taxes. Deferred tax assets and liabilities are determined based on the expected future tax consequences of temporary differences between the Company’s financial statement carrying amounts and the tax basis of assets and liabilities using enacted tax rates expected to be in effect in the years in which the differences are expected to reverse. The Company currently maintains a 100% valuation allowance on its deferred tax assets. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Comprehensive Loss </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Comprehensive loss is defined as the change in equity of a business enterprise during a period from transactions and other events and circumstances from <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-owner</div> sources. Changes in unrealized gains and losses on marketable securities represent the only difference between the Company’s net loss and comprehensive loss.</div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Basic and Diluted Loss Per Common Share </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Basic net loss per share is computed using the weighted average number of common shares outstanding during the period, excluding restricted stock that has been issued but is not yet vested. Diluted net loss per common share is computed using the weighted average number of common shares outstanding and the weighted average dilutive potential common shares outstanding using the treasury stock method. However, for the nine months ended September 30, 2019 and 2018, diluted net loss per share is the same as basic net loss per share because the inclusion of weighted average shares of unvested restricted common stock, common stock issuable upon the exercise of stock options, and common stock issuable upon the conversion of preferred stock would be anti-dilutive. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The following table summarizes outstanding securities not included in the computation of diluted net loss per common share, as their inclusion would be anti-dilutive: </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 72%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Three and Nine Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 1pt;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Common Stock Options </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,461,237 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,123,582 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unvested Restricted Common Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">52,063 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Preferred Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Recent Accounting Pronouncements</div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">In February 2016, the FASB issued ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02,</div> “Leases,” which, together with amendments comprising ASC 842, requires lessees to identify arrangements that should be accounted for as leases and generally recognized, for operating and finance leases with terms exceeding twelve months, a <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">right-of-use</div> asset (or “ROU”) and lease liability on the balance sheet. For public business entities,</div><div style="text-align: left; font-family: Times New Roman; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02</div> is effective for annual and interim reporting periods beginning after December 15, 2018, with early adoption permitted. A modified retrospective transition approach is required, applying the new standard to all leases existing at the date of initial application. The Company adopted ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02</div> effective January 1, 2019. There was no significant retrospective impact from the adoption. The new standard provides a number of optional practical expedients in transition. We have elected the package of practical expedients, which permits us not to reassess under the new standard our prior conclusions about lease identification, lease classification and initial direct costs. The new standard also provides practical expedients for an entity’s ongoing accounting. We have elected the short-term lease exception and we will not recognize ROU assets or lease liabilities for qualifying leases (leases with a term of less than 12 months from lease commencement). In 2019, the Company accounted for a new lease under the guidance (see Note <div style="letter-spacing: 0px; top: 0px;;display:inline;">8</div>).</div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 6pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Principle of Consolidation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The consolidated financial statements include the financial statements of the Company and its wholly owned subsidiaries. All significant intercompany balances have been eliminated in consolidation. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Use of Estimates </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The preparation of financial statements in conformity with GAAP requires management to make estimates and assumptions that affect certain reported amounts of assets and liabilities, and the reported amounts of revenues and expenses during the reporting periods. The Company bases its estimates on historical experience and various other assumptions that management believes to be reasonable under the circumstances. Changes in estimates are recorded in the period in which they become known. Actual results could ​​​​​​​differ from those estimates. </div></div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and Cash Equivalents </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company considers all highly liquid investments with original maturities of three months or less at the date of purchase to be cash equivalents. The Company maintains its cash in bank accounts, the balance of which, at times, exceeds Federal Deposit Insurance Corporation insured limits. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The primary objective of the Company’s investment activities is to preserve its capital for the purpose of funding operations and the Company does not enter into investments for trading or speculative purposes. The Company’s cash is deposited in highly rated financial institutions in the United States. The Company invests in money market funds and high-grade, commercial paper and corporate bonds, which management believes are subject to minimal credit and market risk. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: 12pt;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable Securities </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Marketable securities consist of investments in high-grade corporate obligations and government and government agency obligations that are classified as <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale.</div> Since these securities are available to fund current operations, they are classified as current assets on the consolidated balance sheets.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;">The Company adjusts the cost of <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> debt securities for amortization of premiums and accretion of discounts to maturity. The Company includes such amortization and accretion as a component of interest income, net. Realized gains and losses and declines in value, if any, that the Company judges to be other-than-temporary on <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> securities are reported as a component of interest income, net. To determine whether an other-than-temporary impairment exists, the Company considers whether it intends to sell the debt security and, if the Company does not intend to sell the debt security, it considers available evidence to assess whether it is more likely than not that it will be required to sell the security before the recovery of its amortized cost basis. During the three and nine months ended September 30, 2019 and 2018, the Company determined it did not have any securities that were other-than-temporarily impaired.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities are stated at fair value, including accrued interest, with their unrealized gains and losses included as a component of accumulated other comprehensive income or loss, which is a separate component of stockholders’ equity. The fair value of these securities is based on quoted prices and observable inputs on a recurring basis. Realized gains and losses are determined on the specific identification method. During the three and nine months ended September 30, 2019 and 2018, the Company did not have any realized gains or losses on marketable securities. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair Value of Financial Instruments </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The carrying amounts of the Company’s financial instruments, which include cash equivalents, and marketable securities, approximate their fair values. The fair value of the Company’s financial instruments reflects the amounts that would be received upon sale of an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The fair value hierarchy has the following three levels: </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 1—quoted prices in active markets for identical assets and liabilities. </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 2—observable inputs other than Level 1 inputs. Examples of Level 2 inputs include quoted prices in active markets for similar assets or liabilities and quoted prices for identical assets or liabilities in markets that are not active. </div></div><div style="text-align: left; text-indent: 0%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px; margin-left: 4%;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Level 3—unobservable inputs that reflect the Company’s own assumptions about the assumptions market participants would use in pricing the asset or liability. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Financial assets and liabilities are classified in their entirety within the fair value hierarchy based on the lowest level of input that is significant to the fair value measurement. The Company measures the fair value of its marketable securities by taking into consideration valuations obtained from third-party pricing sources. The pricing services utilize industry standard valuation models, including both income and market based approaches, for which all significant inputs are observable, either directly or indirectly, to estimate fair value. These inputs include reported trades of and broker-dealer quotes on the same or similar securities, issuer credit spreads, benchmark securities and other observable inputs. As of September 30, 2019, the Company’s financial assets valued based on Level 1 inputs consisted of cash and cash equivalents in a money market fund and its financial assets valued based on Level 2 inputs consisted of high-grade corporate bonds and commercial paper. During the three and nine months ended September 30, 2019 and 2018, the Company did not have any transfers of financial assets between Levels 1 and 2. As of September 30, 2019 and December 31, 2018, the Company did not have any financial liabilities that were recorded at fair value on a recurring basis on the balance sheet. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Research and Development Costs </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Research and development costs are expensed as incurred. Research and development costs are comprised of costs incurred in performing research and development activities, including internal costs (including stock-based compensation), costs for consultants, milestone payments under licensing agreements, and other costs associated with the Company’s preclinical and clinical programs. In particular, the Company has conducted safety studies in animals, optimized and implemented the manufacturing of our drug, and conducted Phase <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">1-3</div> clinical trials, all of which are considered research and development expenditures. Significant judgment and estimates are made in determining the amount of research and development costs recognized in each reporting period. The Company analyzes the progress of its clinical trials, completion of milestones under its license agreements, invoices received and contracted costs when estimating research and development costs. Actual results could differ from the Company’s estimates. The Company’s historical estimates for research and development costs have not been materially different from the actual costs.</div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Patents </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Costs to secure and defend patents are expensed as incurred and are classified as general and administrative expense in the Company’s consolidated statements of operations. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-Based Compensation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">The Company recognizes stock-based compensation expense based on the grant date fair value of stock options granted to employees, officers, and directors. The Company uses the Black-Scholes option pricing model to determine the grant date fair value as management believes it is the most appropriate valuation method for its option grants. The Black-Scholes model requires inputs for risk-free interest rate, dividend yield, volatility and expected lives of the options. The expected lives for options granted represent the period of time that options granted are expected to be outstanding. The Company uses the simplified method for determining the expected lives of options. Expected volatility is based upon an industry estimate or blended rate including the Company’s historical trading activity. The risk-free rate for periods within the expected life of the option is based on the U.S. Treasury yield curve in effect at the time of the grant. The Company estimates the forfeiture rate based on historical data. This analysis is <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">re-evaluated</div> at least annually and the forfeiture rate is adjusted as necessary.</div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Certain of the employee stock options granted by the Company are structured to qualify as incentive stock options (“ISOs”). Under current tax regulations, the Company does not receive a tax deduction for the issuance, exercise or disposition of ISOs if the employee meets certain holding requirements. If the employee does not meet the holding requirements, a disqualifying disposition occurs, at which time the Company may receive a tax deduction. The Company does not record tax benefits related to ISOs unless and until a disqualifying disposition is reported. In the event of a disqualifying disposition, the entire tax benefit is recorded as a reduction of income tax expense. The Company has not recognized any income tax benefit for its share-based compensation arrangements due to the fact that the Company does not believe it is more likely than not it will realize the related deferred tax assets. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Income Taxes </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company uses the asset and liability method to account for income taxes. Deferred tax assets and liabilities are determined based on the expected future tax consequences of temporary differences between the Company’s financial statement carrying amounts and the tax basis of assets and liabilities using enacted tax rates expected to be in effect in the years in which the differences are expected to reverse. The Company currently maintains a 100% valuation allowance on its deferred tax assets. </div></div> 1 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Comprehensive Loss </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">Comprehensive loss is defined as the change in equity of a business enterprise during a period from transactions and other events and circumstances from <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-owner</div> sources. Changes in unrealized gains and losses on marketable securities represent the only difference between the Company’s net loss and comprehensive loss.</div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Basic and Diluted Loss Per Common Share </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Basic net loss per share is computed using the weighted average number of common shares outstanding during the period, excluding restricted stock that has been issued but is not yet vested. Diluted net loss per common share is computed using the weighted average number of common shares outstanding and the weighted average dilutive potential common shares outstanding using the treasury stock method. However, for the nine months ended September 30, 2019 and 2018, diluted net loss per share is the same as basic net loss per share because the inclusion of weighted average shares of unvested restricted common stock, common stock issuable upon the exercise of stock options, and common stock issuable upon the conversion of preferred stock would be anti-dilutive. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The following table summarizes outstanding securities not included in the computation of diluted net loss per common share, as their inclusion would be anti-dilutive: </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 72%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Three and Nine Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 1pt;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Common Stock Options </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,461,237 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,123,582 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unvested Restricted Common Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">52,063 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Preferred Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The following table summarizes outstanding securities not included in the computation of diluted net loss per common share, as their inclusion would be anti-dilutive: </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 72%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Three and Nine Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 1pt;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Common Stock Options </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,461,237 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,123,582 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unvested Restricted Common Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">52,063 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Preferred Stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,969,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> 1461237 1461237 1123582 1123582 52063 52063 1969797 1969797 1969797 1969797 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Recent Accounting Pronouncements</div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">In February 2016, the FASB issued ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02,</div> “Leases,” which, together with amendments comprising ASC 842, requires lessees to identify arrangements that should be accounted for as leases and generally recognized, for operating and finance leases with terms exceeding twelve months, a <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">right-of-use</div> asset (or “ROU”) and lease liability on the balance sheet. For public business entities,</div><div style="text-align: left; font-family: Times New Roman; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt;">ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02</div> is effective for annual and interim reporting periods beginning after December 15, 2018, with early adoption permitted. A modified retrospective transition approach is required, applying the new standard to all leases existing at the date of initial application. The Company adopted ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02</div> effective January 1, 2019. There was no significant retrospective impact from the adoption. The new standard provides a number of optional practical expedients in transition. We have elected the package of practical expedients, which permits us not to reassess under the new standard our prior conclusions about lease identification, lease classification and initial direct costs. The new standard also provides practical expedients for an entity’s ongoing accounting. We have elected the short-term lease exception and we will not recognize ROU assets or lease liabilities for qualifying leases (leases with a term of less than 12 months from lease commencement). In 2019, the Company accounted for a new lease under the guidance (see Note <div style="letter-spacing: 0px; top: 0px;;display:inline;">8</div>).</div> true <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">3. Liquidity and Uncertainties </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company is subject to risks common to development stage companies in the biopharmaceutical industry including, but not limited to, uncertainty of product development and commercialization, dependence on key personnel, uncertainty of market acceptance of products and product reimbursement, product liability, uncertain protection of proprietary technology, potential inability to raise additional financing necessary for development and commercialization, and compliance with the U.S. Food and Drug Administration and other government regulations. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company has incurred losses since inception, including approximately $56.2 million for the nine months ended September 30, 2019, resulting in an accumulated deficit of approximately $195.5 million as of September 30, 2019. Management expects to incur losses for the foreseeable future. To date, the Company has funded its operations primarily through the issuance of convertible debt, the proceeds from the Merger on July 22, 2016, and proceeds from sales of the Company’s equity securities. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company believes that its cash, cash equivalents and marketable securities at September 30, 2019 will be sufficient to fund operations past one year from the issuance of these financial statements. To meet its future capital needs, the Company intends to raise additional capital through debt or equity financings, collaborations, partnerships or other strategic transactions. However, there can be no assurance that the Company will be able to complete any such transactions on acceptable terms or otherwise. The inability of the Company to obtain sufficient funds on acceptable terms when needed could have a material adverse effect on the Company’s business, results of operations and financial condition. The Company has the ability to delay certain research activities and related clinical expenses if necessary due to liquidity concerns until a date when those concerns are relieved. </div></div> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4. Cash, Cash Equivalents and Marketable Securities </div></div></div><div style="text-align: left; text-indent: 0.68in; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">A summary of cash, cash equivalents and <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> marketable securities held by the Company as of September 30, 2019 and December 31, 2018 is as follows (in thousands):</div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 92%; font-size: 10pt; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 62%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="14" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">September 30, 2019 </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 1pt;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cost </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>gains </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>losses </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair </div></div></div><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">value </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and cash equivalents: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,975 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"> —  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"> —  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,975 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Money market funds (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">87,511 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">87,511 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 3 months of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash and cash equivalents </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89,486 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89,486 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 year of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">278,707 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">264 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(9</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">278,962 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 to 2 years of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">85,125 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">59 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(22</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">85,162 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash, cash equivalents and marketable securities </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">453,318 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">323 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(31</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">453,610 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> <table border="0" cellpadding="0" cellspacing="0" style="width: 92%; font-size: 10pt; margin-right: auto; margin-left: auto; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 65%; padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="14" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">December 31, 2018 </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cost </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>gains </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>losses </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair </div></div></div><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">value </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and cash equivalents: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,004 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,004 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Money market funds (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">43,401 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">43,401 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 3 months of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11,974 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11,974 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash and cash equivalents </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">57,379 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">57,379 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 year of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">426,658 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(333</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">426,339 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash, cash equivalents and marketable securities </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">484,037 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(333</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">483,718 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> <div style="text-align: left; text-indent: 0.68in; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">A summary of cash, cash equivalents and <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">available-for-sale</div> marketable securities held by the Company as of September 30, 2019 and December 31, 2018 is as follows (in thousands):</div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 92%; font-size: 10pt; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 62%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="14" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">September 30, 2019 </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 1pt;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cost </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>gains </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>losses </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; border-bottom: 1pt solid rgb(0, 0, 0);"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair </div></div></div><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">value </div></div></div></td> <td style="padding: 0px 2pt 1pt 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and cash equivalents: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,975 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"> —  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"> —  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,975 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Money market funds (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">87,511 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">87,511 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 3 months of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash and cash equivalents </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89,486 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89,486 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 year of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">278,707 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">264 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(9</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">278,962 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 to 2 years of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">85,125 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">59 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(22</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">85,162 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 1px solid rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 1px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash, cash equivalents and marketable securities </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">453,318 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">323 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(31</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">453,610 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0in; font-family: &quot;Times New Roman&quot;; border-bottom: 3px double rgb(0, 0, 0);"> </td> <td style="padding: 0px 2pt 3px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> <table border="0" cellpadding="0" cellspacing="0" style="width: 92%; font-size: 10pt; margin-right: auto; margin-left: auto; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 65%; padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="14" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">December 31, 2018 </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cost </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>gains </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrealized<br/>losses </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Fair </div></div></div><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">value </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash and cash equivalents: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Cash (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,004 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,004 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Money market funds (Level 1) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">43,401 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">43,401 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 3 months of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11,974 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11,974 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash and cash equivalents </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">57,379 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">57,379 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Marketable securities: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Corporate debt securities due within 1 year of date of purchase (Level 2) </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">426,658 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(333</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">426,339 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total cash, cash equivalents and marketable securities </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">484,037 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(333</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">483,718 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> 1975000 1975000 87511000 87511000 P3M 89486000 89486000 P1Y 278707000 264000 9000 278962000 P1Y P2Y 85125000 59000 22000 85162000 453318000 323000 31000 453610000 2004000 2004000 43401000 43401000 P3M 11974000 11974000 57379000 57379000 P1Y 426658000 14000 333000 426339000 484037000 14000 333000 483718000 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">5. Accrued Liabilities </div></div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Accrued liabilities as of September 30, 2019 and December 31, 2018 consisted of the following (in thousands): </div></div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 73%; padding: 0px;"/> <td style="width: 8%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 8%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">September 30,<br/>2019 </div></div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"> </div></div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">December 31,<br/>2018 </div></div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"> </div></div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Accrued contract research costs </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">7,882 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">571 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Compensation and benefits </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,936 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,797 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Other </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,563 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">3,589 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal; background: none;"/></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14,381 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">5,957 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Accrued liabilities as of September 30, 2019 and December 31, 2018 consisted of the following (in thousands): </div></div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 73%; padding: 0px;"/> <td style="width: 8%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 8%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">September 30,<br/>2019 </div></div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"> </div></div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">December 31,<br/>2018 </div></div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"><div style="font-weight:bold;display:inline;"> </div></div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Accrued contract research costs </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">7,882 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">571 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Compensation and benefits </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,936 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,797 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Other </div></div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,563 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">3,589 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal; background: none;"/></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">14,381 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">$</div></td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">5,957 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom;"><div style="background: none; letter-spacing: 0px; top: 0px;;display:inline;"> </div></td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> 7882000 571000 1936000 1797000 4563000 3589000 14381000 5957000 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">6</div>. Stockholders’ Equity </div></div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 6pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Common Stock </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Each common stockholder is entitled to one vote for each share of common stock held. The common stock will vote together with all other classes and series of stock of the Company as a single class on all actions to be taken by the Company’s stockholders. Each share of common stock is entitled to receive dividends, as and when declared by the Company’s board of directors. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company has never declared cash dividends on its common stock and does not expect to do so in the foreseeable future. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Preferred Stock </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">The Series A Preferred Stock has a par value of $0.0001 per share and is convertible into shares of the common stock at a <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">one-to-one<div style="letter-spacing: 0px; top: 0px;;display:inline;"> </div></div>ratio,<div style="letter-spacing: 0px; top: 0px;;display:inline;"> </div><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">subject to adjustment as provided in the Certificate of Designation of Preferences, Rights and Limitations of Series A Convertible Preferred Stock, that the Company filed with the Secretary of State of the State of Delaware on June 21, 2017 (the “Series A Certificate”). The terms of the Series A Preferred Stock are set forth in the Series A Certificate.</div></div> Each share of the Series A Preferred Stock is convertible into shares of Common Stock following notice that may be given at the holder’s option. Upon any liquidation, dissolution or <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">winding-up</div> of the Company, whether voluntary or involuntary, after the satisfaction in full of the debts of the Company and the payment of any liquidation preference owed to the holders of shares of capital stock of the Company ranking prior to the Series A Preferred Stock upon liquidation, the holders of the Series A Preferred Stock shall participate pari passu with the holders of the Common Stock (on an <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;"><div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">as-if-converted-to</div>-Common-Stock</div> basis) in the net assets of the Company. Shares of the Series A Preferred Stock will generally have no voting rights, except as required by law. Shares of the Series A Preferred Stock will be entitled to receive dividends before shares of any other class or series of capital stock of the Company (other than dividends in the form of the Common Stock) equal to the dividend payable on each share of the Common Stock, on an <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">as-converted</div> basis.</div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-style: normal; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-style:italic;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">June 2018 Registered Offering of Common Stock </div></div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">In June 2018, the Company entered into an underwriting agreement with Goldman Sachs &amp; Co. LLC, as representative of the several underwriters named therein (the “June 2018 Underwriters”), relating to an underwritten public offering (the “June 2018 Offering”) of 1,079,580 shares of the Company’s common stock, including 95,973 shares of the Company’s common stock purchased by the June 2018 Underwriters pursuant to a <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">30-day</div> option to purchase such additional shares granted therein, at a public offering price of $305.00 per share. The June 2018 Offering resulted in net proceeds to the Company of approximately $311.8 million, after deducting the June 2018 Underwriters’ discount and other offering costs. The June 2018 Offering closed on June 11, 2018.</div> 1 0.0001 1 0 1079580 95973 305.00 311800000 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">7</div>. Stock-based Compensation </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">The 2015 Stock Plan, as amended, is our primary plan through which equity ​​​​​​​based grants are awarded. We ceased making new awards under the 2006 Stock Plan upon adoption of the 2015 Stock Plan. The 2015 Stock Plan provides for the grant of incentive stock options, <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-statutory</div> stock options, restricted stock and other stock-based compensation awards to employees, officers, directors, and consultants of the Company. The administration of the 2015 Stock Plan is under the general supervision of the Compensation Committee of the Board of Directors. The terms of stock options awarded under the 2015 Stock Plan, in general, are determined by the Compensation Committee, provided the exercise price per share generally shall not be set at less than the fair market value of a share of the common stock on the date of grant and the term shall not be greater than ten years from the date the option is granted. As of September 30, 2019, the Company had options outstanding to purchase 1,461,237 shares of its common stock, which includes options outstanding under its 2006 Stock Plan. As of September 30, 2019, 1,352,095 shares were available for future issuance.</div><div style="text-align: left; text-indent: 4%; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px; line-height: 12pt;"><div style="letter-spacing: 0px; font-size: 10pt; top: 0px;;display:inline;">The following table summarizes stock option activity during the nine months ended September 30, 2019:</div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 77%; padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Shares </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/>average<br/>exercise<br/>price </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at January 1, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,132,618 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">48.52 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options granted </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">369,500 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">119.29 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options exercised </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(20,131</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11.67 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options cancelled </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(20,750</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">173.79 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,461,237 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">65.15 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Exercisable at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">922,149 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">40.55 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The total cash received by the Company as a result of stock option exercises was $0.2 million and $1.9 million, respectively, for the nine months ended September 30, 2019 and 2018. The weighted-average grant date fair values, based on the Black-Scholes option model, of options granted during the nine months ended September 30, 2019 and 2018 were $91.65 and $136.43, respectively. </div></div><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-style: normal; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-style:italic;display:inline;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Restricted Common Stock </div></div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company’s share-based compensation plan provides for awards of restricted shares of common stock to employees, officers, directors and consultants to the Company. Restricted stock awards are subject to forfeiture if employment or service terminates during the prescribed retention period. Restricted shares vest over the service period. </div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The following table summarizes unvested restricted share activity during the nine months ended September 30, 2019: </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 80%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Shares </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/>average<br/>exercise<br/>price </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at January 1, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">52,063 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">9.45 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Vested </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(52,063</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">9.45 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0px; line-height: 12pt;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-Based Compensation Expense </div></div></div><div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-based compensation expense during the three and nine months ended September 30, 2019 and 2018 was as follows (in thousands): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 92%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 59%; padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Three Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Nine Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-based compensation expense by type of award: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock options </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,922 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,852 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,455 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,002 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Restricted stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">28 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">124 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">272 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">368 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total stock-based compensation expense </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,950 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,976 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,727 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,370 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Effect of stock-based compensation expense by line item: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Research and development </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,404 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,179 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">6,647 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,287 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">General and administrative </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,546 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">3,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">12,080 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">6,083 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total stock-based compensation expense included in net loss </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,950 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,976 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,727 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,370 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table> <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 12pt; margin-bottom: 0pt; line-height: 12pt;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrecognized stock-based compensation expense as of September 30, 2019 was as follows (in thousands): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 76%; padding: 0px;"> </td> <td style="width: 7%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="width: 7%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> </tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrecognized<br/> stock<br/> compensation<br/> expense </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/> average<br/> remaining<br/> period<br/> (in years) </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock options </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">35,429 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2.86 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Restricted stock </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—    </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">35,429 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2.86 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> </table> <div style="clear: both; max-height: 0px;"> </div> 1461237 1352095 <div style="text-align: left; text-indent: 4%; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px; line-height: 12pt;"><div style="letter-spacing: 0px; font-size: 10pt; top: 0px;;display:inline;">The following table summarizes stock option activity during the nine months ended September 30, 2019:</div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 77%; padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 4%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Shares </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/>average<br/>exercise<br/>price </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at January 1, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,132,618 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">48.52 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options granted </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">369,500 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">119.29 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options exercised </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(20,131</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">11.67 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Options cancelled </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(20,750</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">173.79 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,461,237 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">65.15 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Exercisable at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">922,149 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">40.55 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/><div style="clear: both; max-height: 0px;"/> 1132618 48.52 369500 119.29 20131 11.67 20750 173.79 1461237 65.15 922149 40.55 200000 1900000 91.65 136.43 <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The following table summarizes unvested restricted share activity during the nine months ended September 30, 2019: </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 80%; padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 5%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Shares </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/>average<br/>exercise<br/>price </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at January 1, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">52,063 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">9.45 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Vested </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">(52,063</div></div></td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; white-space: nowrap; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">)</td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">9.45 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Outstanding at September 30, 2019 </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table> 52063 9.45 52063 9.45 0 0 <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-based compensation expense during the three and nine months ended September 30, 2019 and 2018 was as follows (in thousands): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 92%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 59%; padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="width: 6%; padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/> <td style="padding: 0px;"/></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Three Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td colspan="6" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Nine Months Ended September 30, </div></div></div></td> <td style="padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td></tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2018 </div></div></div></td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock-based compensation expense by type of award: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock options </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,922 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,852 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,455 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,002 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Restricted stock </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">28 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">124 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">272 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">368 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total stock-based compensation expense </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,950 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,976 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,727 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,370 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Effect of stock-based compensation expense by line item: </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Research and development </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,404 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">1,179 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">6,647 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,287 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">General and administrative </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2,546 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">3,797 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">12,080 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">6,083 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"><div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total stock-based compensation expense included in net loss </div></div></td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,950 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">4,976 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">18,727 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"><div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8,370 </div></div></td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td></tr></table> 4922000 4852000 18455000 8002000 28000 124000 272000 368000 4950000 4976000 18727000 8370000 2404000 1179000 6647000 2287000 2546000 3797000 12080000 6083000 4950000 4976000 18727000 8370000 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 12pt; margin-bottom: 0pt; line-height: 12pt;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrecognized stock-based compensation expense as of September 30, 2019 was as follows (in thousands): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 76%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 76%; padding: 0px;"> </td> <td style="width: 7%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="width: 7%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> </tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Unrecognized<br/> stock<br/> compensation<br/> expense </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Weighted<br/> average<br/> remaining<br/> period<br/> (in years) </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Stock options </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">35,429 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2.86 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Restricted stock </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—    </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 3em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">35,429 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2.86 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 3px double rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> </table> <div style="clear: both; max-height: 0px;"> </div> 35429000 P2Y10M9D 35429000 P2Y10M9D <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">8</div>. Leases </div></div></div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">In 2019, the Company entered into an operating lease for office space. As described within Note 2, we adopted ASU <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">2016-02, </div> “Leases,” on January 1, 2019 requiring, among other changes, operating and finance leases with terms exceeding twelve months to be recognized as ROU assets and lease liabilities on the balance sheet. Operating lease ROU assets and operating lease liabilities are recognized based on the present value of the future minimum lease payments over the lease term at the commencement date. The lease term is determined to be the <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">non-cancelable</div> period including any lessee renewal options that are considered reasonably certain of exercise. The interest rate implicit in lease contracts is typically not readily determinable. As such, the Company used judgment to determine an appropriate incremental borrowing rate, which is the rate incurred to borrow on a collateralized basis over a similar term in a similar economic environment.</div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Future minimum payments under the Company’s operating leases related to the ROU asset and lease liability as of September 30, 2019 was as follows (in thousand): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 68%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 87%; padding: 0px;"> </td> <td style="width: 10%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> </tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Operating </div></div></div> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Leases </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2020 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">363 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2021 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">371 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2022 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">31 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Thereafter </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total minimum payments </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">854 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Less: imputed interest </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">103 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Present value of lease liabilities </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">751 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> </table> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">As of September 30, 2019, the weighted average remaining operating lease term was 2.3 years and the weighted average discount rate used to determine the operating lease liabilities was 5.5%. Operating lease costs were $93 thousand and $267 thousand, short-term lease costs were $23 thousand and $138 thousand, and there were no variable lease costs for the three and nine months ended September 30, 2019, respectively. </div></div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Future minimum payments under the Company’s operating leases related to the ROU asset and lease liability as of September 30, 2019 was as follows (in thousand): </div></div> <table border="0" cellpadding="0" cellspacing="0" style="margin: 12pt auto 0px; width: 68%; font-size: 10pt; border-collapse: collapse; border-spacing: 0px;"> <tr style="font-size: 0px;"> <td style="width: 87%; padding: 0px;"> </td> <td style="width: 10%; padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> <td style="padding: 0px;"> </td> </tr> <tr style="font-size: 8pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal; background: none;"/> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td colspan="2" style="vertical-align: bottom; border-bottom: 1pt solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Operating </div></div></div> <div style="text-align: center; font-family: &quot;Times New Roman&quot;; font-size: 8pt; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Leases </div></div></div> </td> <td style="padding: 0px 2pt 0px 0px; font-weight: normal; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom;"><div style="font-weight:bold;display:inline;"> </div></td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2019 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">89 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2020 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">363 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2021 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">371 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">2022 </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">31 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Thereafter </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">—  </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Total minimum payments </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">854 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid; background-color: rgb(204, 238, 255);"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Less: imputed interest </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> </td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">103 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 0pt; page-break-inside: avoid;"> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="vertical-align: bottom; border-bottom: 1px solid rgb(0, 0, 0); padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="padding: 0px 2pt 0px 0px; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> <tr style="font-size: 10pt; page-break-inside: avoid;"> <td style="padding: 0px; vertical-align: top;"> <div style="text-align: left; text-indent: -1em; font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; margin-left: 1em; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">Present value of lease liabilities </div></div> </td> <td style="vertical-align: top; padding-left: 0px; padding-top: 0px; padding-bottom: 0px; font-family: &quot;Times New Roman&quot;;"> </td> <td style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;">$</td> <td style="text-align: right; vertical-align: bottom; padding-left: 0px; padding-top: 0px; padding-bottom: 0px;"> <div style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; margin-top: 0pt; margin-bottom: 0pt; line-height: normal;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">751 </div></div> </td> <td style="padding: 0px 2pt 0px 0px; margin-top: 0pt; margin-bottom: 0pt; vertical-align: bottom; font-family: &quot;Times New Roman&quot;;"> </td> </tr> </table> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> <div style="clear: both; max-height: 0px;"> </div> 89000 363000 371000 31000 854000 103000 751000 P2Y3M18D 0.055 93000 267000 23000 138000 0 0 <div style="text-align: left; font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-weight: normal; margin-top: 18pt; margin-bottom: 0px;"><div style="font-weight:bold;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">9</div>. Commitments and Contingencies </div></div></div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 6pt; margin-bottom: 0px;">The Company has a Research, Development and Commercialization Agreement with <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">Hoffmann-La</div> Roche (“Roche”) which grants the Company a sole and exclusive license to develop, use, sell, offer for sale and import any Licensed Product as defined by the agreement.</div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;">The agreement requires future milestone payments to Roche. In 2019, the Company commenced a Phase 3 study in <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">Non-Alcoholic</div> Steatohepatitis (NASH), which triggered a $2 million milestone payment under the agreement. Remaining milestones under the agreement total $8 million and are earned by achieving specified objectives related to future regulatory approval in the United States and Europe of a product developed from <div style="white-space: nowrap; letter-spacing: 0px; top: 0px;;display:inline;">MGL-3196</div> (resmetirom). A single-digit royalty payment range is based on net sales of products developed from resmetirom, subject to certain reductions. Except as described above, the Company has not achieved any additional product development or regulatory milestones and had no Licensed Product sales for the nine months ended September 30, 2019 and 2018.</div> <div style="text-align: left; text-indent: 4%; font-family: Times New Roman; font-size: 10pt; margin-top: 12pt; margin-bottom: 0px;"><div style="letter-spacing: 0px; top: 0px;;display:inline;">The Company has entered into customary contractual arrangements and letters of intent in preparation for and in support of the Phase 3 clinical trials. </div></div> 2000000 8000000 0 0