UNITED STATES | OMB APPROVAL |
SECURITIES AND EXCHANGE COMMISSION | OMB Number:        3235-0101 |
Washington, D.C. 20549 | Expires:      December 31, 2009 |
| Estimated average burden |
FORM 144 | hours per response ......... 2.00 |
NOTICE OF PROPOSED SALE OF SECURITIES | SEC USE ONLY |
PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933 | DOCUMENT SEQUENCE NO. |
ATTENTION: Transmit for filing 3 copies of this form concurrently with either placing | CUSIP NUMBER |

an order with a broker to execute sale or executing a sale directly with
                           a market maker.

I (a) NAME OF ISSUER (Please type or print) SYNTA PHARMACEUTICALS CORPORATION | (b) IRS IDENT. NO. | (c) S.E.C. FILE NO. | | WORK LOCATION |
1 (d) ADDRESS OF ISSUER | STREET | CITY | STATE | ZIP CODE | | (e) TELEPHONE NO.
| | | | | | AREA CODE | NUMBER
45 | HARTWELL AVENUE, | LEXINGTON | MA | 02421 | | |
2 (a) NAME OF PERSON FOR WHOSE ACCOUNT THE SECURITIES ARE TO BE SOLD | | (b) RELATIONSHIP TO ISSUER | (c) ADDRESS STREET | CITY | STATE | ZIP CODE
GALLEON TECHNOLOGY OFFSHORE, Ltd. | | NONE | 590 MADISON AVE., 34th, FL | NY | NY | 10022
INSTRUCTION: The person filing this notice should contact the issuer to obtain the I.R.S. Identification Number and the S.E.C. File Number.
3 (a) | (b) | SEC USE ONLY | (c) | (d) | (e) | (f) | (g)

Title of the
Class of
Securities
To Be Sold

Name and Address of Each Broker Through
Whom the Securities are to be Offered
or Each Market Maker who is Acquiring
the Securities

Broker-Dealer
File Number

Number of Shares
or Other Units
To Be Sold
(See instr. 3(c))

Aggregate
Market
Value
(See instr, 3(d))

Number of Shares
or Other Units
Outstanding
(See instr. 3(e))

Approximate
Date of Sale
(See instr. 3(f))
(MO. DAY YR.)

Name of Each
Securities
Exchange
(See instr. 3(g))

COMMON | KNIGHT EQUITY MARKETS, L.P. 545 WASHINGTON BOULEVARD JERSEY CITY, NEW JERSEY 07310 | | 13,577 | 110,657.98 | 33,832,198 | 11/9/07 | NASDAQ

INSTRUCTIONS: | 3. | (a) | Title of the class of securities to be sold
1. | (a) (b) | Name of issuer Issuer’s I.R.S. Identification Number | | (b) | Name and address of each broker through whom the securities are intended to be sold
| (c) (d) | Issuer’s S.E.C. file number, if any Issuer’s address, including zip code | | (c) | Number of shares or other units to be sold (if debt securities, give the aggregate face amount)
| (e) | Issuer’s telephone number, including area code | | (d) | Aggregate market value of the securities to be sold as of a specified date within 10 days prior to the filing of this notice
| | | | (e) | Number of shares or other units of the class outstanding, or if debt securities the face amount thereof outstanding, as shown by the most recent report or statement published by the issuer
| | | | (f) (g) | Approximate date on which the securities are to be sold Name of each securities exchange, if any, on which the securities are intended to be sold

2.

(a)
(b)

Name of person for whose account the securities are to be sold
Such person’s relationship to the issuer (e.g., officer, director,
10% stockholder, or member of immediate family of any of
the foregoing)

| (c) | Such person’s address, including zip code | | |
| Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. |

TABLE I -  SECURITIES SOLD TO BE SOLD

Furnish the following information with respect to the acquisition of the securities to be sold
and with respect to the payment of all or any part of the purchase price or other consideration therefor:

Title of the Class

Date You Acquired

Nature of Acquisition Transaction

Name of Person from Whom Acquired
(If gift, also give date donor acquired)

Amount of
Securities Acquired

Date of
Payment

Nature of
Payment

COMMON

6/2/06

GALLEON TECHNOLOGY OFFSHORE, Ltd.
 PURCHASED SERIES A CONVERTIBLE
 PREFERRED STOCK ON JUNE 2,2006. THE COMPANY CONVERTED
 THE SERIES A ON FEB. 9, 2007 TO COMMON IN CONNECTION WITH
 THE IPO.

SYNTA PHARMACEUTICALS
 CORPORATION

13,577

6/2/06

CASH

INSTRUCTIONS: | If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given.  If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid. |
TABLE II  -  SECURITIES SOLD DURING THE PAST 3 MONTHS
Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

Name and Address of Seller

Title of Securities Sold

Date of Sale

Amount of       
Securities Sold

Gross Proceeds

GALLEON TECHNOLOGY OFFSHORE, Ltd.
590 MADISION AVENUE, 34TH FLOOR
NY, NY 10022

COMMON

OCT. 10, 2007

48,750

$460,861

REMARKS: | |
INSTRUCTIONS: | | ATTENTION:
See the definition of “person” in paragraph (a) of Rule 144.  Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition.  In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice. | | The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed.
| NOVEMBER 13, 2007 | | | | /S/ CAROLYN A. MILLER |
DATE OF NOTICE | | (SIGNATURE)

The notice shall be signed by the person for whose account the securities are to be sold.  At least one copy of the notice shall be manually signed.
Any copies not manually signed shall bear typed or printed signatures.

ATTENTION:    Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)